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    Eylea 8mg logo
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    Eylea 8mg logo
    Overview
    Indication
    expand_more
    nAMD
    DME
    Mode of Action
    Safety
    Dosing
    Injection guidance
    OcuClick

    We're for those who want the simplicity of OcuClick®

    How to use OcuClick, the EYLEA® 8mg (aflibercept 114.3 mg/mL, solution for injection) pre-filled syringe

    Key steps for preparing and injecting OcuClick

    Discover the new and innovative EYLEA 8mg pre-filled syringe, OcuClick. We listened, we designed and we delivered a syringe for more precise and simple injections. Below, you will find key steps to prepare for an injection. Always consult the OcuClick instructions here for more detailed steps.

    Learn the key steps in the OcuClick training animation

    It is important to handle the syringe using aseptic technique.

    Inspect the syringe visually before use for any foreign particulate matter and/or unusual colour (the solution can be pale yellow,
which is normal), or any variation in physical appearance. If any of these are observed, do not use the product.
     

    Administer EYLEA® (aflibercept) 8mg with a simple priming process

    Steps 1 to 6
    Step 1: Snap off syringe cap

    Snap off (do not twist off) the syringe cap by holding the syringe in one hand and the syringe cap with the thumb and forefinger of the other hand.

    Do not pull back on the plunger.

    Step 2: Attach needle

    Firmly twist the 30 G x ½ inch injection needle onto the Luer-lock syringe tip.
     

    Step 3: Dislodge air bubbles

    Hold the syringe with the needle pointing up. Check the solution for bubbles. If there are bubbles, gently tap the syringe with your finger until the bubbles rise to the top.

    Step 4: Expel air and excess volume to prime

    The syringe does not have a dose line because it is designed to set the dose mechanically.

    The pre-filled syringe contains more volume than the recommended dose (70μL).

    To eliminate all bubbles, keep syringe upright and vertical, and to expel excess drug, slowly depress the plunger rod until it stops, i.e. until the guide on the plunger rod reaches the finger grip.

    Step 5: Set to dose

    Turn the end of the plunger rod 90 degrees clockwise or counterclockwise until the guide of the plunger rod aligns with the slot. You may hear or feel a click.


    The device is now ready to dose. Do not push the plunger rod before insertion into the eye.


    When ready to administer EYLEA 8mg, remove the plastic needle shield.

    Step 6: Administer the injection

    Insert the needle into the ocular injection site.
Inject the solution by pushing in the plunger
 rod until it stops, i.e. until the guide is
completely within the slot. Do not apply additional pressure once the guide is within the slot. After the injection, it is normal to see a small amount of residual solution left in the syringe.

    The pre-filled syringe is for single use in one eye only. Any unused product or waste material
should be disposed of in accordance with
local requirements.

    Explore
    Safety
    Explore the EYLEA 8mg safety data in nAMD and DME patients
    Dosing
    Discover the posology of EYLEA 8mg
    Why a higher dose of EYLEA?
    Learn more about the EYLEA Mode of Action
    • Abbreviationsexpand_more

      DME, diabetic macular oedema.

      MoA, mechanism of action.

      nAMD, neovascular (wet) age-related macular degeneration.

    First Page
    Overview

    • Referencesexpand_less
      • 1
        EYLEA® (aflibercept solution for injection) Summary of Product Characteristics. Berlin, Germany: Bayer Pharma AG.