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How to use OcuClick, the EYLEA® 8mg (aflibercept 114.3 mg/mL, solution for injection) pre-filled syringe
Discover the new and innovative EYLEA 8mg pre-filled syringe, OcuClick. We listened, we designed and we delivered a syringe for more precise and simple injections. Below, you will find key steps to prepare for an injection. Always consult the OcuClick instructions here for more detailed steps.
It is important to handle the syringe using aseptic technique.
Inspect the syringe visually before use for any foreign particulate matter and/or unusual colour (the solution can be pale yellow,
which is normal), or any variation in physical appearance. If any of these are observed, do not use the product.
Administer EYLEA® (aflibercept) 8mg with a simple priming process
Snap off (do not twist off) the syringe cap by holding the syringe in one hand and the syringe cap with the thumb and forefinger of the other hand.
Do not pull back on the plunger.
Firmly twist the 30 G x ½ inch injection needle onto the Luer-lock syringe tip.
Hold the syringe with the needle pointing up. Check the solution for bubbles. If there are bubbles, gently tap the syringe with your finger until the bubbles rise to the top.
The syringe does not have a dose line because it is designed to set the dose mechanically.
The pre-filled syringe contains more volume than the recommended dose (70μL).
To eliminate all bubbles, keep syringe upright and vertical, and to expel excess drug, slowly depress the plunger rod until it stops, i.e. until the guide on the plunger rod reaches the finger grip.
Turn the end of the plunger rod 90 degrees clockwise or counterclockwise until the guide of the plunger rod aligns with the slot. You may hear or feel a click.
The device is now ready to dose. Do not push the plunger rod before insertion into the eye.
When ready to administer EYLEA 8mg, remove the plastic needle shield.
Insert the needle into the ocular injection site. Inject the solution by pushing in the plunger rod until it stops, i.e. until the guide is completely within the slot. Do not apply additional pressure once the guide is within the slot. After the injection, it is normal to see a small amount of residual solution left in the syringe.
The pre-filled syringe is for single use in one eye only. Any unused product or waste material should be disposed of in accordance with local requirements.
- Abbreviationsexpand_more
DME, diabetic macular oedema.
MoA, mechanism of action.
nAMD, neovascular (wet) age-related macular degeneration.
- Referencesexpand_less
- 1EYLEA® (aflibercept solution for injection) Summary of Product Characteristics. Berlin, Germany: Bayer Pharma AG.